The Gene Ontology Handbook edited by Christophe and Nives is out! Download the whole book or individual chapters freely at SpringerLink (open access).


  1. 2017
  2. Georgia Tsagkogeorga, Steven Müller, Christophe Dessimoz, Stephen J. Rossiter
    Comparative genomics reveals contraction in olfactory receptor genes in bats
    Scientific Reports, 2017, 7:259
  3. Daniel C Jeffares, Clemency Jolly, Mimoza Hoti, Doug Speed, Charalampos Rallis, Christophe Dessimoz*, Jürg Bähler*, Fritz Sedlazeck* (*joint corresponding)
    Transient structural variations alter gene expression and quantitative traits in Schizosaccharomyces pombe
    Nature Communications, 2017, 8:14061 Story behind the paper
  4. Pascale Gaudet, Nives Škunca, James C. Hu, Christophe Dessimoz
    Primer on the Gene Ontology
    The Gene Ontology Handbook (C Dessimoz, N Škunca, Eds.),
    Methods in Molecular Biology, 2017, Springer (New York), Vol. 1446
  5. Pascale Gaudet and Christophe Dessimoz
    Gene Ontology: pitfalls, biases, remedies
    The Gene Ontology Handbook (C Dessimoz, N Škunca, Eds.),
    Methods in Molecular Biology, 2017, Springer (New York), Vol. 1446
  6. Alexander Warwick Vesztrocy and Christophe Dessimoz
    Gene Ontology tutorial in Python
    The Gene Ontology Handbook (C Dessimoz, N Škunca, Eds.),
    Methods in Molecular Biology, 2017, Springer (New York), Vol. 1446
  7. Christophe Dessimoz and Nives Škunca, Editors
    The Gene Ontology Handbook
    Methods in Molecular Biology, 2017, Springer (New York), Vol. 1446
  8. 2016
  9. Yuxiang Jiang et al (147 authors including Adrian Altenhoff, Nives Škunca and Christophe Dessimoz)
    An expanded evaluation of protein function prediction methods shows an improvement in accuracy
    Genome Biology, 2016, 17:184
  10. Sojo Victor, Christophe Dessimoz, Andrew Pomiankowski and Nick Lane
    Membrane proteins are dramatically less conserved than water-soluble proteins across the tree of life
    Molecular Biology and Evolution, advanced access Supplementary data
  11. Natasha M. Glover, Ioanna Antoniadi, Gavin M. George, Lars Götzenberger, Ruben Gutzat, Kadri Koorem, Pierre Liancourt, Kinga Rutowicz, Krishna Saharan, Wanhui You and Philipp Mayer
    A Pragmatic Approach to Getting Published: 35 Tips for Early Career Researchers
    Frontiers in Plant Science, 2016, 7:610
  12. Oscar Robinson*, David Dylus*, Christophe Dessimoz (*equal contributions) interactive viewing and comparison of large phylogenetic trees on the web
    Molecular Biology and Evolution, 2016, 33:8, 2163-2166 Project page Git repo Story behind the paper Demo video
  13. Fabian Zimmer, Peter W Harrison, Christophe Dessimoz, Judith Mank
    Compensation of dosage-sensitive genes on the chicken Z chromosome
    Genome Biology and Evolution, 2016, 8:4, 1233-1242
  14. Adrian Altenhoff, (25 co-authors including Daniel A. Dalquen and Clément-Marie Train), Christophe Dessimoz
    Standardized benchmarking in the quest for orthologs
    Nature Methods, 2016, 13, 425–430 Story behind the paper Project page
  15. Natasha Glover, Henning Redestig, Christophe Dessimoz
    Homoeologs: what are they and how do we infer them?
    Trends in Plant Science, 2016, 21, 609–621 Story behind the paper
  16. Kevin Gori, Tomasz Suchan, Nadir Alvarez, Nick Goldman, Christophe Dessimoz
    Clustering genes of common evolutionary history
    Molecular Biology and Evolution, 2016, 33:6, 1590-1605 Git repo Raw data Blog post
  17. 2015
  18. Ge Tan, Matthieu Muffato, Christian Ledergerber, Javier Herrero, Nick Goldman, Manuel Gil, Christophe Dessimoz
    Current methods for automated filtering of multiple sequence alignments frequently worsen single-gene phylogenetic inference
    Systematic Biology, 2015, 64:5, 778-791 Supplementary data Story behind the paper
  19. Matt Ravenhall*, Nives Škunca*, Florent Lasalle, Christophe Dessimoz (*equal contributions)
    Inferring horizontal gene transfer
    PLOS Computational Biology, 2015, 11:5, e1004095 On Wikipedia Story behind the paper
  20. Bernhard Egger*, François Lapraz*, Bartłomiej Tomiczek*, Steven Müller, Christophe Dessimoz, Johannes Girstmair, Nives Škunca, Kate A Rawlinson, Christopher B Cameron, Elena Beli, M Antonio Todaro, Mehrez Gammoudi, Carolina Noreña, Maximilian J Telford (*co-first)
    A transcriptomic-phylogenomic analysis of the evolutionary relationships of flatworms
    Current Biology, 2015, 25:10, 1347–1353
  21. Nives Škunca and Christophe Dessimoz
    Phylogenetic profiling: how much input data is enough?
    PLOS One, 2015, 10:2, e0114701
  22. Ge Tan, Manuel Gil, Ari P Löytynoja, Nick Goldman, Christophe Dessimoz
    Simple chained guide trees give poorer multiple sequence alignments than inferred trees in simulation and phylogenetic benchmarks
    PNAS, 2015, 112:2, E99-E100 Preprint Raw data
  23. Adrian M Altenhoff, Nives Škunca, Natasha Glover, Clément-Marie Train, Anna Sueki, Ivana Piližota, Kevin Gori, Bartlomiej Tomiczek, Steven Müller, Henning Redestig, Gaston H Gonnet and Christophe Dessimoz
    The OMA orthology database in 2015: function predictions, better plant support, synteny view, and other improvements
    Nucleic Acids Res, 2015, 43:D1, D240-D249 Project page
  24. 2014
  25. Xinxia Peng et al. (38 authors including Kevin Gori, Nives Škunca, and Christophe Dessimoz)
    The draft genome sequence of the ferret (Mustela putorius furo) facilitates study of human respiratory disease
    Nature Biotechnology, 2014, 32:12, 1250-1255
  26. Lucas D Wittwer*, Ivana Piližota*, Adrian M Altenhoff, Christophe Dessimoz (*equal contributions)
    Speeding up all-against-all protein comparisons while maintaining sensitivity by considering subsequence-level homology
    PeerJ, 2014, 2:e607 Story behind the paper
  27. Erik Sonnhammer, Toni Gabaldón, Alan WS da Silva, Maria Martin, Marc Robinson-Rechavi, Brigitte Boeckmann, Paul Thomas, Christophe Dessimoz, and the Quest for Orthologs consortium
    Big data and other challenges in the quest for orthologs
    Bioinformatics, 2014, 30:21, 2993-2998
  28. Maria Anisimova and Christophe Dessimoz
    Preface of Proceedings of GNOME 2014 -- Festschrift for Gaston Gonnet
    PeerJ PrePrints, 2014, 2:e426v1 GNOME 2014 Festschrift
  29. Diana Coman, Adrian M Altenhoff, Stefan Zoller, Wilhelm Gruissem and Eva Vranová
    Distinct evolutionary strategies in the GGPPS family from plants
    Frontiers in Plant Science, 2014, 5:230
  30. Heinz Stockinger, Adrian M Altenhoff, Arnold K, Konstantin Arnold, Amos Bairoch, Frederic Bastian, Sven Bergmann, et al.
    Fifteen years SIB Swiss Institute of Bioinformatics: life science databases, tools and support
    Nucleic Acids Res, 2014, 42(W1): W436-W441
  31. Stefano Iantorno*, Kevin Gori*, Nick Goldman, Manuel Gil, Christophe Dessimoz (*equal contributions)
    Who watches the watchmen? an appraisal of benchmarks for multiple sequence alignment
    Multiple Sequence Alignment Methods (D Russell, Editor),
    Methods in Molecular Biology, 2014, Springer Humana, Vol. 1079. Preprint
  32. 2013
  33. Christophe Dessimoz, Nives Škunca, Paul D. Thomas
    CAFA and the open world of protein function predictions
    Trends in Genetics, 2013, 29:11, 609-610
  34. Ajay Prasad, Suchitra Suresh Kumar, Christophe Dessimoz, Vincent Jaquet, Stefan Bleuler, Oliver Laule, Tomas Hruz, Wilhelm Gruissem, Philip Zimmermann
    Global regulatory architecture of human, mouse and rat tissue transcriptomes
    BMC Genomics, 2013, 14:716
  35. Daniel A. Dalquen and Christophe Dessimoz
    Bidirectional best hits miss many orthologs in duplication-rich clades such as plants and animals
    Genome Biology and Evolution, 2013, 5:10, 1800-1806
  36. Daniel A. Dalquen, Adrian M Altenhoff, Gaston H. Gonnet, Christophe Dessimoz
    The impact of gene duplication, insertion, deletion, lateral gene transfer and sequencing error on orthology inference: a simulation study
    PLoS One, 2013, 8:2, e56925 Datasets
  37. Nick Goldman, Paul Bertone, Siyuan Chen, Christophe Dessimoz, Emily M. LeProust, Botond Sipos, Ewan Birney
    Towards practical, high-capacity, low-maintenance information storage in synthesized DNA
    Nature, 2013, 494:7435, 77-80 Media coverage Full text (PMC)
  38. Adrian M Altenhoff, Manuel Gil, Gaston H. Gonnet, Christophe Dessimoz
    Inferring hierarchical orthologous groups from orthologous gene pairs
    PLoS One, 2013, 8:1, e53786 Software
  39. Mikael Sunnåker, Alberto G Busetto*, Elina Numminen*, Jukka Corander, Matthieu Foll, Christophe Dessimoz (*equal contributions)
    Approximate Bayesian computation
    PLoS Computational Biology, 2013, 9:1, e1002803 On Wikipedia Story behind the paper
  40. 2012
  41. Nives Škunca, Adrian M Altenhoff, Christophe Dessimoz
    Quality of computationally inferred gene ontology annotations
    PLoS Computational Biology, 2012, 8:5, e1002533 Interactive plots Story behind the paper
  42. Adrian M Altenhoff, Romain Studer, Marc Robinson-Rechavi, Christophe Dessimoz
    Resolving the ortholog conjecture: orthologs tend to be weakly, but significantly, more similar in function than paralogs
    PLoS Computational Biology, 2012, 8:5, e1002514 Press release Story behind the paper
  43. Christophe Dessimoz, Toni Gabaldón, David S Roos, Erik LL Sonnhammer, Javier Herrero, and the Quest for Orthologs Consortium
    Toward community standards in the quest for orthologs
    Bioinformatics, 2012, 28:6, 900-904
  44. Adrian M Altenhoff and Christophe Dessimoz
    Inferring Orthology and Paralogy
    Evolutionary Genomics: Statistical and Computational methods (M Anisimova, Editor),
    Methods in Molecular Biology, 2012, Springer Humana, Vol. 855. PDF
  45. Daniel A. Dalquen, Maria Anisimova, Gaston H. Gonnet, Christophe Dessimoz
    ALF - A Simulation Framework for Genome Evolution
    Molecular Biology and Evolution, 2012, 29:4, 1115-1123
  46. 2011
  47. Christophe Dessimoz
    Editorial: Orthology and Applications
    Briefings in Bioinformatics, 2011, 12:5, 375-376 PDF Special Issue
  48. Christophe Dessimoz, Stefan Zoller, Tereza Manousaki, Huan Qiu, Axel Meyer, Shigehiro Kuraku
    Comparative genomics approach to detecting split coding regions in a low-coverage genome: lessons from the chimaera Callorhinchus milii (Holocephali, Chondrichthyes)
    Briefings in Bioinformatics, 2011, 12:5, 423-435 Software
  49. Brigitte Boeckmann, Marc Robinson-Rechavi, Ioannis Xenarios, Christophe Dessimoz
    Conceptual Framework and Pilot Study to Benchmark Phylogenomic Databases Based on Reference Gene Trees
    Briefings in Bioinformatics, 2011, 12:5, 474-484
  50. Maria Anisimova, Manuel Gil, Jean-François Dufayard, Christophe Dessimoz, Olivier Gascuel
    Survey of Branch Support Methods Demonstrates Accuracy, Power, and Robustness of Fast Likelihood-based Approximation Schemes.
    Systematic Biology, 2011, 60:5, 685-699
  51. Judith Owiti, Jonas Grossmann, Peter Gehrig, Christophe Dessimoz, Christophe Laloi, Maria Ben Hansen, Wilhelm Gruissem, Hervé Vanderschuren
    iTRAQ-based analysis of changes in the cassava root proteome reveals pathways associated with post-harvest physiological deterioration
    The Plant Journal, 2011, 67:1, 145-156
  52. Louis du Plessis, Nives Škunca, Christophe Dessimoz
    The What, Where, How, and Why of Gene Ontology -- A Primer for Bioinformaticians
    Briefings in Bioinformatics, 2011, 12:6, 723-735
  53. Christian Ledergerber and Christophe Dessimoz
    Base-Calling for Next-Generation Sequencing Platforms
    Briefings in Bioinformatics, 2011, 12:5, 489-497
  54. Adrian M Altenhoff, Adrian Schneider, Gaston H. Gonnet, Christophe Dessimoz
    OMA 2011: Orthology Inference Among 1,000 Complete Genomes
    Nucleic Acids Research, 2011, 39 (suppl 1): D289-D294 Project page
  55. 2010
  56. Christophe Dessimoz* and Manuel Gil* (*equal contributions)
    Phylogenetic assessment of alignments reveals neglected tree signal in gaps
    Genome Biology, 2010, 11:R37 Raw data
  57. 2009
  58. Toni Gabaldón, Christophe Dessimoz, Julie Huxley-Jones, Albert J Vilella, Erik LL Sonnhammer, Suzanna Lewis
    Joining forces in the quest for orthologs
    Genome Biology 2009, 10:403
  59. Alexandre Gattiker, Christophe Dessimoz, Adrian Schneider, Ioannis Xenarios, Marco Pagni, Jacques Rougemont
    The Microbe Browser for Comparative Genomics
    Nucleic Acids Research, 2009, 37 (suppl 2): W296-W299. Project page
  60. Adrian M Altenhoff and Christophe Dessimoz
    Phylogenetic and Functional Assessment of Orthologs Inference Projects and Methods
    PLoS Computational Biology, 2009, 5:1, e1000262
  61. 2008
  62. Alexander Roth, Gaston H. Gonnet, Christophe Dessimoz
    Algorithm of OMA for Large-Scale Orthology Inference
    BMC Bioinformatics, 2008, 9:518
    (Please note the associated erratum)
    Project page
  63. Mark T. Holder, Derrick J. Zwickl, Christophe Dessimoz
    Evaluating the Robustness of Phylogenetic Methods to Among-Site Variability in Substitution Processes
    Phil. Trans. R. Soc. B, 2008, 363:1512, 4013-4021
  64. Adam M Szalkowski, Christian Ledergerber, Philipp Krähenbühl, Christophe Dessimoz
    SWPS3 - Fast Multi-Threaded Vectorized Smith-Waterman for IBM Cell/B.E. and x86/SSE2
    BMC Research Notes, 2008, 1:107 Project page
  65. Christophe Dessimoz* and Manuel Gil* (*equal contributions)
    Covariance of Maximum Likelihood Evolutionary Distances between Sequences Aligned Pairwise
    BMC Evolutionary Biology, 2008, 8:179
  66. Christophe Dessimoz, Daniel Margadant, Gaston H. Gonnet
    DLIGHT - Lateral Gene Transfer Detection Using Pairwise Evolutionary Distances in a Statistical Framework
    RECOMB 2008, LNCS 4955, 315-330 PDF
  67. 2007
  68. Christian Ledergerber and Christophe Dessimoz
    Alignments with Non-overlapping Moves, Inversions and Tandem Duplications in O(n4) time
    COCOON 2007, LNCS 4598, 151-164 PDF Abstract
    selected for publication in Journal of Combinatorial Optimization, 2008, 16:3 PDF
  69. Adrian Schneider, Christophe Dessimoz, Gaston H. Gonnet
    OMA Browser - Exploring orthologous relations across 352 complete genomes
    Bioinformatics, 2007, 23:16, 2180-2182 Project page
  70. 2006
  71. Christophe Dessimoz, Manuel Gil, Adrian Schneider, Gaston H. Gonnet
    Fast Estimation of the Difference between two PAM/JTT Evolutionary Distances in Triplets of Homologous Sequences
    BMC Bioinformatics, 2006, 7:529
  72. Christophe Dessimoz, Brigitte Boeckmann, Alexander Roth, Gaston H. Gonnet
    Detecting Non-Orthology in the COGs Database and Other Approaches Grouping Orthologs Using Genome-Specific Best Hits
    Nucleic Acids Res, 2006 34:11, 3309-3316
  73. 2005
  74. Manuel Gil, Christophe Dessimoz, Gaston H. Gonnet
    A Dimensionless Fit Measure for Phylogenetic Distance Trees
    J Bioinform Comput Biol, 2005, 3:6, 1429-1440
  75. Christophe Dessimoz, Gina Cannarozzi, Manuel Gil, Daniel Margadant, Alexander Roth, Adrian Schneider, Gaston H. Gonnet
    OMA, a Comprehensive, Automated Project for the Identification of Orthologs from Complete Genome Data: Introduction and First Achievements
    RECOMB 2005 Workshop on Comparative Genomics, LNCS 3678, 61-72 PDF Project page
Last modified on March 21st, 2017.